3-oxo-2-(3-oxo-5-sulfo(1h-benzo[d]azolin-2-ylidene))-1h-benzo[d]azoline-5-sulf Onic Acid, Sodium Salt, Sodium Salt, 164. Disodium 5,5'-(2-(1,3-dihydro-3-oxo-2h-indazol-2-ylidene)-1,2-dihydro-3h-indol-3-one)disulphonate, 108. InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;; C1=CC2=C(C=C1S(=O)(=O)[O-])C(=O)C(=C3C(=O)C4=C(N3)C=CC(=C4)S(=O)(=O)[O-])N2.[Na+]. Follow the directions on your prescription label carefully. ... 4 patients ... had facial color changes to a blue-green-gray color and decreased oxygen saturation as measured by pulse oximetry. 1h-indole-5-sulfonic Acid,2-(1,3-dihydro-3-oxo-5-sulfo-2h-indol-2-ylidene)- 2,3-dihydro-3-oxo-,disodium Salt, 162. All rights reserved. Disclaimer: This information is independently developed by CIMS based on indigo carmine from various references and is provided for your reference only. These usually cause no problems and frequently go undetected unless the patient is monitored closely during that brief interval. However, recently /they/ encountered sudden and severe hypotension following the intravenous injection of IC in 7 patients undergoing radical retropubic prostatectomy ... nausea, Shir Y, Raja SN; Anesthesiology 79 (3): 378-81 (1993). Indigo-5,5 Inverted Exclamation Marka-disulfonic Acid Disodium Salt, 157. The authors note that they/ routinely use IC during urologic operations ... and in most patients, mild hypertension and bradycardia appear immediately after its injection. Hammann B.; Anaesthesist 38 (3): 136-9 (1989). Tell your doctor all medications and supplements you use. This rare complication and the duration of tissue discoloration have never been described. V04CH02 - Indigo carmine < V04CH - Tests for renal function and ureteral injuries < V04C - Other diagnostic agents < V04 - Diagnostic agents < V - Various. Chemicals and substances that impart color including soluble dyes and insoluble pigments. You should consult with a medical professional if you have any questions about your health. Indigo carmine (indigotin disulfonate sodium) is usually used as a marker dye to locate the ureteral orifice, severed ureters, or fistulas (1). following (use any or all that apply): Indigo Carmine is available in the following doses: Enter multiple addresses on separate lines or separate them with commas. It has a role as a food colouring and a histological dye. Disodium Salt Of 1-indigotin-s,s'-disulfonic Acid, 117. Indigo carmine is not recommended during pregnancy and in women of childbearing potential not using contraception. Indigo carmine was metabolized by cecal microflora /of rats/ to four [corrected] fluorescent metabolites with Rf values of 0.09, 0.27, 0.5 and 0.72 ... disodium;(2E)-3-oxo-2-(3-oxo-5-sulfonato-1H-indol-2-ylidene)-1H-indole-5-sulfonate. The intravenous method is preferred because a 5 mL injection is sufficient. All information on this site is provided "as-is" for informational purposes only and is not a substitute for medical advice or treatment. Indigo Carmine Drug Class. Back to Top. Disodium 2-(1,3-dihydro-3-oxo-5-sulfo-2h-indol-2-ylidene)-2,3-dihydro-3-oxo-1h-indole-5-sulfonate, 102. Although the mechanism for hypotension with IC is unclear, we should be aware that IC, when given vaginally as well as IV, could cause severe hypotension. Carmine (disodium Indigo-5,5-disulfonate), 154. Disodium (2e)-3-oxo-2-(3-oxo-5-sulfonato-1h-indol-2-ylidene)-1h-indole-5-sulfonate, 161. Ask your doctor or pharmacist for more information. Indigo Disulfonate (biological Stain), 113. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. 2-(1,3-dihydro-3-oxo-5-sulpho-2h-indol-2-ylidene)-3- Oxoindoline-5-sulphonic Acid, 10. Graziano S et al; Int Urogynecol J Pelvic Floor Dysfunct 16 (5): 418-9 (2005). Tests for renal function and ureteral injuries, Indigo Carmine 8 Mg/ml Injectable Solution. CIMS Class . Ng TY et al; J Urol 116 (1): 132-3 (1976). Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Copyright © 2020 CIMS. 2-(1,3-dihydro-3-oxo-5-sulfo-2h-indol-2-ylidene)-2,3-dihydro-3-oxo-1h-indole-5-sulfonic Ac Id, Disodium Salt, 163. Breast-feeding. 1h-indole-5-sulfonic Acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2h-indol-2-ylidene)-2,3-dihydro-3-oxo-, Disodium Salt, 98. Hence, the effects of intravascularly injected indigo carmine on hemodynamics are variable and difficult to anticipate ... ... A case of severe life-threatening anaphylactoid reaction followed by cardiac arrest associated with intravenous indigo carmine injection /is described/. Patient 1 received an intravenous (IV) methylene blue solution during a urologic procedure, and the remaining three patients were administered subcutaneous indigo carmine (patient 2) or Patent Blue (Patients 3 and 4) for axillary lymph node mapping.